This video is part 1 of Innate immunity – Classification and General Factors Content: Introduction: 0:00 Classification of the Innate Immune System 1:08 General Factors of the Innate immunity 3:00 ——————————- —————————————————————————- All information in my immunology videos are from: – Book: Immunology, Eighth Edition by David Male, Jonathan Brostoff, David Roth and Ivan Roitt – Additional research in PubMed – University lecture materials ——————————————————————————– Difference between innate and acquired immunity: Innate: – Non-specific – No immunological memory – Attacks all agents equally Acquired: – Specific defense – Gain immunological memory Classification of innate immunity: 1. General factors: – Barriers (Skin and Gastrointestinal tract) – Pyrogenic reactions (Fever) – Secretion 2. Cellular Factors – Microbiota – Phagocytosis – Natural Killer Cells – Toll Like receptors – Inflammation reaction 3. Humoral Factors – Complement System – Interferons General Factors: Skin: – Physical Barrior – Because of tight junctions – Secretion of products Mucous Membranes: – Lysozyme, Pepsin, Defensins, low pH